Detalhe da pesquisa
1.
Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy.
Cell
; 175(3): 766-779.e17, 2018 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30340042
2.
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.
Cell
; 150(3): 575-89, 2012 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863010
3.
Prenol, but Not Vitamin C, of Fruit Binds to SARS-CoV-2 Spike S1 to Inhibit Viral Entry: Implications for COVID-19.
J Immunol
; 210(12): 1938-1949, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37144841
4.
Discovery of a small-molecule inhibitor of the TRIP8b-HCN interaction with efficacy in neurons.
J Biol Chem
; 298(7): 102069, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35623388
5.
Selective Inhibition of the Interaction between SARS-CoV-2 Spike S1 and ACE2 by SPIDAR Peptide Induces Anti-Inflammatory Therapeutic Responses.
J Immunol
; 207(10): 2521-2533, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34645689
6.
Identification of a druggable protein-protein interaction site between mutant p53 and its stabilizing chaperone DNAJA1.
J Biol Chem
; 296: 100098, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33208462
7.
Correction: Selective Inhibition of the Interaction between SARS-CoV-2 Spike S1 and ACE2 by SPIDAR Peptide Induces Anti-Inflammatory Therapeutic Responses.
J Immunol
; 212(10): 1602, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38536099
8.
Discovery of covalent enzyme inhibitors using virtual docking of covalent fragments.
Bioorg Med Chem Lett
; 29(1): 36-39, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30455147
9.
Modeling MEK4 Kinase Inhibitors through Perturbed Electrostatic Potential Charges.
J Chem Inf Model
; 59(10): 4460-4466, 2019 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31566378
10.
Discovery of a novel class of potent and selective tetrahydroindazole-based sigma-1 receptor ligands.
Bioorg Med Chem
; 27(9): 1824-1835, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30904383
11.
Identification and characterization of PPARα ligands in the hippocampus.
Nat Chem Biol
; 12(12): 1075-1083, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27748752
12.
Catalytic, Enantioselective ß-Protonation through a Cooperative Activation Strategy.
J Org Chem
; 82(9): 4689-4702, 2017 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28441019
13.
In Silico Modeling-based Identification of Glucose Transporter 4 (GLUT4)-selective Inhibitors for Cancer Therapy.
J Biol Chem
; 290(23): 14441-53, 2015 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25847249
14.
Mutagenesis studies of the H5 influenza hemagglutinin stem loop region.
J Biol Chem
; 289(32): 22237-45, 2014 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24947513
15.
Enantioselective ß-Protonation by a Cooperative Catalysis Strategy.
J Am Chem Soc
; 137(18): 5891-4, 2015 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25929160
16.
Enantioselective annulations for dihydroquinolones by in situ generation of azolium enolates.
J Am Chem Soc
; 136(30): 10589-92, 2014 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25017004
17.
Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C.
Sci Adv
; 9(10): eadf2468, 2023 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36888719
18.
Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models.
J Clin Invest
; 133(6)2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36719747
19.
Knot theory in understanding proteins.
J Math Biol
; 65(6-7): 1187-213, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22105789
20.
Druggable sites/pockets of the p53-DNAJA1 protein-protein interaction: In silico modeling and in vitro/in vivo validation.
Methods Enzymol
; 675: 83-107, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36220282